Abstract
Purpose
Integrating genomic data into the electronic health record (EHR) is key for optimally
delivering genomic medicine.
Methods
The PennChart Genomics Initiative (PGI) at the University of Pennsylvania is a multidisciplinary
collaborative that has successfully linked orders and results from genetic testing
laboratories with discrete genetic data in the EHR. We quantified the use of the genomic
data within the EHR, performed a time study with genetic counselors, and conducted
key informant interviews with PGI members to evaluate the effect of the PGI’s efforts
on genetics care delivery.
Results
The PGI has interfaced with 4 genetic testing laboratories, resulting in the creation
of 420 unique computerized genetic testing orders that have been used 4073 times to
date. In a time study of 96 genetic testing activities, EHR use was associated with
significant reductions in time spent ordering (2 vs 8 minutes, P < .001) and managing (1 vs 5 minutes, P < .001) genetic results compared with the use of online laboratory-specific portals.
In key informant interviews, multidisciplinary collaboration and institutional buy-in
were identified as key ingredients for the PGI’s success.
Conclusion
The PGI’s efforts to integrate genomic medicine into the EHR have substantially streamlined
the delivery of genomic medicine.
Keywords
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Article info
Publication history
Published online: September 15, 2022
Accepted:
August 15,
2022
Received in revised form:
August 15,
2022
Received:
February 18,
2022
Identification
Copyright
© 2022 American College of Medical Genetics and Genomics. Published by Elsevier Inc. All rights reserved.
