Advertisement

Addendum: Statement on nutritional supplements and piracetam for children with Down syndrome

  • Manisha Balwani
    Affiliations
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai New York NY USA

    American College of Medical Genetics and Genomics Bethesda MD USA
    Search for articles by this author
  • The American College of Medical Genetics and Genomics (ACMG) Professional Practice and Guidelines Committee
    *
      The original statement was published in the ACMG newsletter in 1996.
      This document was retired by the ACMG Board of Directors as of 27 April 2020 with the following addendum:
      Based on the current literature,
      • Lobaugh N.J.
      • Karaskov V.
      • Rombaugh V.
      • et al.
      Piracetam therapy does not enhance cognitive functioning in children with Down syndrome.
      ,
      • Committee on Genetics.
      Health supervision for children with Down syndrome.
      the use of piracetam or other nutritional supplements in the health supervision for children with Down syndrome is not recommended.

      Additional information

      Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

      References

        • Lobaugh N.J.
        • Karaskov V.
        • Rombaugh V.
        • et al.
        Piracetam therapy does not enhance cognitive functioning in children with Down syndrome.
        1:STN:280:DC%2BD3M3ivFCitw%3D%3D
        10.1001/archpedi.155.4.442
        Arch Pediatr Adolesc Med. 2001; 155: 442-448
        • Committee on Genetics.
        Health supervision for children with Down syndrome.
        10.1542/peds.2011-1605
        Pediatrics. 2011; 128 (Reaffirmed in Pediatrics. 2018; 141:e20180518): 393-406