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    • folic acid supplementation1
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    ACMG Statements and Guidelines

    These online statements and guidelines are definitive and may be cited using the digital object identifier (DOI). These recommendations are designed primarily as an educational resource for medical geneticists and other healthcare providers to help them provide quality medical genetics services; they should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. Please refer to the leading disclaimer in each document for more information.

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    • ACMG Practice Guidelines
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      Folic acid and neural tube defects

      Genetics in Medicine
      Vol. 7Issue 4p283–284Published in issue: April, 2005
      • Helga V. Toriello
      • for the Professional Practice and Guidelines Committee
      Cited in Scopus: 16
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        Major congenital anomalies occur in 2% to 3% of live births. Neural tube defects (NTDs), cleft lip and palate, and cardiac anomalies are some of the most common. NTDs are a group of serious birth defects that affect the developing nervous system and include anencephaly, spina bifida, and encephalocele. Birth records suggest that about 2500 babies with these birth defects, or 1 to 2 per 1000, are born each year in the United States. Some affected pregnancies are spontaneously or electively aborted.
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